PREVENTION AND TREATMENT OF OBESITY: WEIGHT LOSS GOALS
PREVENTION AND TREATMENT OF OBESITY: WEIGHT LOSS GOALS
There is strong evidence that weight loss in overweight and obese individuals decreases their risk of diseases, such as heart conditions and diabetes. The general goals of weight loss and management are to reduce body weight, prevent further weight gain, and [...]
Diet Drug Acomplia Sales Disappoint; No Major Improvement Seen Until 2009
Sales of diet drug Acomplia (rimonabant) , available in Europe but not approved in the U.S., have turned into a major disappointment for Sanofi-Aventis, which says it does not expect the situation to significantly improve until new clinical trial results are ready for submission to regulators in [...]
FDA Advisory Panel Says Obese Kids Should Be Included in Drug Trials
A U.S. FDA Advisory Committee reviewing guidelines for weight-loss drug trials appear prepared to call for studies that focus on the effect of anti–obesity drugs on severely obese children Acomplia (rimonabant) .
Acomplia (rimonabant) “This population of patients needs to be studied separately from the [...]
DRUGS APPROVED BY THE FDA FOR WEIGHT LOSS
DRUGS APPROVED BY THE FDA FOR WEIGHT LOSS
Drugs approved for use in weight loss programs can be broken
down into the following categories:
1. Anorexiants (drugs that work on chemicals in the brain)
a. Amphetamines
1. Benzphetamine (Didrex®)
2. Diethylpriopion (Tenuate®; Tenuate Dospan®)
3. Methamphetamine (Desoxyn®)
4. Phentermine (Adipex®; Adipex®-P or Ionamin®)
b. Sibutramine (Meridia®)
2. Lipase Inhibitors (drugs [...]
Dietary Supplements for Weight Loss
Dietary Supplements for Weight Loss
Dietary supplements are popular products for weight loss. These products are often promoted with elaborate advertising campaigns, often using celebrity endorsements that promise consumers they will lose weight and feel wonderful. Many people believe that since these products are “natural,” they are safe. The reality is that “natural”means [...]
Diet Pills and the FDA
Diet Pills and the FDA
Each year, millions of Americans resolve to lose weight—it is one of the most common New Year’s resolutions. Many people start off with great intentions, but within months, weeks, or even days, most of them give up and return to their usual habits. If they work to lose [...]
Phenylpropanolamine
Phenylpropanolamine
Phenylpropanolamine is similar to amphetamine, but does not cause euphoria and does not have the same potential for abuse. Phenylpropanolamine was used as a cough and cold agent initially, since it relieves congestion associated with the common cold. Before long, people realized that it caused appetite suppression and that they were able to lose [...]
AMPHETAMINE-LIKE WEIGHT LOSS PRODUCTS
AMPHETAMINE-LIKE WEIGHT LOSS PRODUCTS
Amphetamines, which were introduced in 1938, rapidly became the most widely used agents for the treatment of obesity in the United States. Amphetamine (Figure ) is a stimulant that causes the release of the neurotransmitter norepinephrinein the brain, which leads to increased metabolism and increased energy expenditure, or burning of [...]
