Report in The Lancet Further Boosts Interest in Weight-Loss Drug Acomplia

Report in The Lancet Further Boosts Interest in Weight-Loss Drug Acomplia

A published in this week’s issue of the prestigious medical journal, The Lancet, further stoked interest in the promising new Acomplia (rimonabant)  but in fact provided little new information.

The was based on one-year from the RIO-trial, which showed that Acomplia could substantially reduce the waist circumference, and risk factors for heart disease in people.

While this is the first detailed on the Acomplia (rimonabant) trials published in one of the major peer-reviewed medical journals, the data for the most part is old news, since researchers presented two-year data from the RIO-trial at the American College of Cardiology meeting in Orlando in March.

Nevertheless, a number of publications that do not closely track development of this reported on The Lancet article as though it were first-time news.

WebMD, for example, ran a lengthy story on The Lancet headlined: “New May Help Dieters.”

Dr. Luc Van Gaal (University Hospital Antwerp, Belgium), lead researcher in the RIO-trial, reiterated in The Lancet article conclusions similar to those he has p resented orally that “in this treatment with rimonabant over 1 year led to sustained, clinically meaningful reduction in Acomplia (rimonabant) waist circumference, and associated improvements in several cardiovascular and metabolic risk factors.”

In an accompanying editorial in the Lancet, Drs. Uberto Pagotto and Renato Pasquali (Sant Orsola-Malpighi General Hospital, Bologna, Italy) state: “A new pharmacological treatment to tackle and alterations of metabolic and lipid profiles that are often associated, could now be close to practice.

“ These data, and those from the other ongoing trials with rimonabant, might presumably help us to better tackle and related metabolic and cardiovascular disease Acomplia (rimonabant) .

“ When additional drugs are available, we will also have the possibility to individually target the therapeutic strategies according to phenotype characteristics and to the pathophysiological mechanism inducing the disease,” the Italian researchers added.


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